November 27, 2007

Emryonic stem cells - without the embryos

Embryonic stem cells are pluripotent-- they have an almost magical ability to grow into any kind of cell and perform any function. There is a good possibility that some day we may use cells like this to heal injuries and deceases. Until recently, the only way to get these cells was to remove them from the cells of a embryo, a process that is fatal to the embryo and controversial to many.

It was reported on November 20 that a method was developed for making pluripotent stem cells from ordinary skin cells, with no need for an embryo. Two different scientific teams developed the method independently, using specialized viruses to deliver four genes to the skin cell's genetic code. Adding four genes is all it takes to make a embryonic-like stem cell from a skin cell.

Anytime genes are added to normal cells, there is a risk that the cells can grow cancerous. But, researchers are confident that they will soon find a way to switch the cell's genes instead of adding to them, removing the cancer risk.

Having a method for making pluripotent stem cells without using embryos will extinguish the controversy that beleaguers stem cell research. "People working on ethics will have to find something new to worry about," says stem cell researcher Jose Cibelli of Michigan State University. link

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